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Meg Ryan has published a heartfelt tribute to the late filmmaker Rob Reiner, under whose direction she worked in the beloved romantic comedy When Harry Met Sally.

A Tragic Discovery

Reiner was located lifeless with his wife, Michele Singer Reiner, at their home in Los Angeles this past weekend.

“How we will long for this man…” Ryan wrote on Instagram, next to an image of them together. “We thank you, Rob and Michele, for your belief in true love, fairy tales, and laughter. Your trust in people's goodness and your love for this nation are remembered.”

Charges Filed

Reiner’s son Nick, 32, is accused of two counts of first-degree murder and was in court today. He’s being detained without the option of bail. It’s been reported that Reiner’s daughter Romy discovered her father deceased.

“I must hold onto hope that their tale doesn't conclude here, that awareness can be heightened from this,” Ryan went on to write. “While uncertain, I suspect they'd wish for a hopeful, compassionate outcome that fosters mutual understanding and peace.”

A Statement from Siblings

Reiner’s other children Jake and Romy released a message today. “Words cannot even begin to describe the unimaginable pain we are experiencing every moment of the day,” they said. “The horrific and devastating loss of our parents, Rob and Michele Reiner, is something that no one should ever experience. Beyond being our mom and dad, they were our dearest friends.”

Peers Pay Their Respects

Ryan’s co-star, Billy Crystal, joined in remembering Reiner via comments shared yesterday together with remarks by Larry David, Martin Short and Albert Brooks.

“No one matched his comic instinct, his dedication to rhythmic dialogue, or his elegant sharpening of drama,” the statement said. “He adored his actors. He elevated his writers. His greatest gift was freedom. If you had an idea, he listened, he brought you into the process. Everyone felt like part of a crew. His direction was a gift, but his legacy is broader.”

An Enduring Filmography

When Harry Met Sally was a critical and commercial success in 1989, grossing more than $93 million worldwide and securing Nora Ephron an Oscar nomination for best original screenplay.

Rob Reiner first encountered Michele Singer Reiner during the production of When Harry Met Sally. The pair were connected through Barry Sonnenfeld, a friend and director.

Reiner’s notable filmography featured classics such as Misery, Stand by Me and The Princess Bride. The director and his wife were married for 36 years.